Description
The MILabs U-OI/CT is a versatile in vivo imaging system that consists of optical imaging and CT imaging modules that can be used in-line or separately. When used in-line the U-OI/CT can produce more accurate, multi-modal datasets that are seamlessly correlated. The modules can also be used independently allowing separate imaging experiments to be performed by multiple researchers using both modalities.
Features:
- Versatile dual-use solution: in-line mode with top-level CT (right) or offline mode on the bench (left)
- Unprecedented localization & quantification: by adopting a non-uniform reconstruction model, CT data from the same animal corrects absorption & scattering per organ for optical imaging
- Industry-leading performance: ultra-high-sensitivity, high-throughput, best-in-class resolution & FOV
- User-friendly design & easy-to-use features, including spectral mixing/fluorescence crosstalk function
- Imaging results repeatable/comparable across other systems (NIST Traceable)
- Upgradeable with PET and/or SPECT modalities
U-OI/CT in-line mode
- 2D planer & 3D/4D tomographic imaging functionalities.
-2D: bioluminescence, fluorescence and Cherenkov
-3D/4D: unique bioluminescence tomographic (BLT) & fluorescence tomographic
(FLT) modes
- Near-infrared laser excitation source ensures minimal absorption & scattering
U-OI off-line mode with standalone U-CT
- 2D planer imaging functionalities.
-2D: bioluminescence, fluorescence and Cherenkov
-High-throughput: able to image up to 10 animals simultaneously
- Adjustable FOV/resolution/throughput
- Enabling parallel use of optical and X-ray CT modules by different research teams/applications
Versatile in vivo optical imaging from 2D to 3D/4D
MILabs offers versatile and powerful optical imaging solutions for a vast variety of preclinical applications ranging from molecular and functional imaging to translational research. The integrated U-OI/CT allows for optical and CT imaging in parallel for dedicated multimodal applications. This allows you to switch freely between in-line and off-line (or benchtop; standalone) modes.
The seamless in-line mode enables 3D/4D OI/CT acquisitions on a single floor standing platform, and offers more accurate reconstruction and quantification of deep tissues and dark organs. Conveniently, the separate benchtop mode is still available for 2D planar optical imaging.
Meanwhile, U-OI can also be installed separately (without CT module) and offers the flexibility to upgrade to U-OI/CT at a later date.
Upgrade with PET/SPECT
Translation of optical imaging results to clinically compatible PET or SPECT data is easily accomplished by adding the desired nuclear modality to the U-OI/CT system thanks to the modular system design. MILabs offers any combination of in-line PET, SPECT, optical, and CT on a single platform. This makes one-to-one translation from optical/anatomical research data to clinically compatible nuclear imaging technologies possible and avoids animal shuttling with inconsistent anesthesia conditions as well as image registration challenges.